In 1929, famed film director Ernst Lubitsch was looking through old screen tests of Broadway performers and spotted MacDonald. The Shuberts, however, would not let her out of her contract to appear in the film, which starred Dix and Helen Kane (the "Boop-boop-a-doop girl"). While MacDonald was appearing in Angela, film star Richard Dix spotted her and had her screen-tested for his film Nothing but the Truth. Her last play was Boom Boom in 1929, with her name above the title the cast included young Archie Leach, who would later become Cary Grant. Shubert, for which she received rave reviews and Angela (1928), which the critics panned. MacDonald also played the lead in her next two plays: Sunny Days in 1928 in her first show for the producers Lee and J.J. Frazee's No, No, Nanette, the show toured extensively, but failed to please the critics when it arrived on Broadway. She finally landed a starring role in Yes, Yes, Yvette in 1927. The following year, 1926, found MacDonald still in a second female lead in Bubblin' Over, a musical version of Brewster's Millions. In 1925, MacDonald again had the second female lead opposite Queenie Smith in Tip Toes, a George Gershwin hit show. MacDonald played the second female lead in this long-running musical which starred Mitzi Hajos. In 1921, MacDonald played in Tangerine as one of the "Six Wives." In 1922, she was a featured singer in the Greenwich Village revue Fantastic Fricassee, for which good press notices brought her a role in The Magic Ring the next year.
In 1920, she appeared in two musicals: Jerome Kern's Night Boat as a chorus replacement, and Irene on the road as the second female lead future film star Irene Dunne played the title role during part of the tour, and Helen Shipman played the title role during the other part of the tour. She took singing lessons with Wassili Leps and landed a job in the chorus of Ned Wayburn's The Demi-Tasse Revue, a musical entertainment presented between films at the Capitol Theatre on Broadway. In November 1919, MacDonald joined her older sister Blossom in New York. MacDonald backstage in a costume for the Broadway show Sunny Days (1928) She later took lessons with Al White and began touring in his kiddie shows, heading his "Six Little Song Birds" in Philadelphia at the age of nine. She began dancing lessons with local dance instructor Caroline Littlefield, mother of American ballerina/choreographer Catherine Littlefield, when very young, performing in juvenile operas, recitals, and, shows staged by Littlefield around the city, including at the Academy of Music. The extra N in her given name was later dropped for simplicity's sake, and A added to her surname to emphasize her Scottish heritage. She was of Scottish, English, and Dutch descent.
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She was the youngest of the three daughters of Anna May (née Wright) and Daniel McDonald, a factory foreman and a salesman for a contracting household building company, respectively, and the younger sister of character actress Blossom Rock (born Edith McDonald), who was most famous as "Grandmama" on the 1960s TV series The Addams Family.
MacDonald was born Jeannette Anna McDonald on June 18, 1903, at her family's Philadelphia home at 5123 Arch Street.
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